If you’re dealing with a stomach or duodenal ulcer, your doctor might mention sucralfate. It’s not an antacid or a proton pump inhibitor. Instead, sucralfate sticks to damaged tissue and forms a protective layer so acid and enzymes can’t keep irritating the sore spot. That simple coating action helps ulcers heal and can ease pain.
Sucralfate is a sugar-aluminum complex. When it hits the acidic stomach, it turns into a sticky paste that clings to ulcers and erosions. Doctors most often prescribe it for active duodenal ulcers and sometimes for gastric ulcers or esophagitis caused by reflux. Because it isn’t absorbed into the bloodstream much, systemic side effects are less common than with some other drugs.
People use sucralfate for short-term ulcer treatment and sometimes to protect the gut in people taking NSAIDs. If you have kidney problems, mention that to your prescriber—aluminum can build up if kidneys don’t clear it well.
Common practice is to take sucralfate on an empty stomach—usually about 1 hour before meals and at bedtime. Tablets or liquid are both options; the liquid can coat better but needs measuring. A typical schedule many doctors use is four times a day, but your provider will tell you the right dose for your case. Don’t crush extended-release forms unless the label says it’s okay.
Sucralfate can bind other medicines and reduce their effect. That means you should separate many drugs by about two hours. Drugs commonly affected include certain antibiotics (like ciprofloxacin), digoxin, phenytoin, levothyroxine, and warfarin. Antacids may change sucralfate’s action, so follow your prescriber’s timing instructions.
Side effects are usually mild. The most common is constipation. Some people report an upset stomach, dry mouth, or dizziness. Serious allergic reactions are rare, but if you get rash, swelling, or trouble breathing, seek help right away.
Want to buy sucralfate online? Make sure the pharmacy is legitimate. Look for a verified pharmacy, a clear address, and a way to contact a pharmacist. Many countries require a prescription for sucralfate—don’t skip that step. Beware of sites that sell medications without asking for a prescription or that offer prices that look too good to be true.
Finally, ask your clinician about pregnancy, breastfeeding, or kidney disease before starting sucralfate. If your symptoms don’t improve within a few weeks, or if you have worsening pain, vomiting, weight loss, or black stools, contact your provider. Sucralfate can help protect and heal, but it’s one part of a treatment plan that should fit your health needs.
Sucralfate is emerging as a leading treatment for gastric ulcers. This article breaks down its effectiveness, how it works, potential benefits, and important considerations. Learn why this medication is becoming the first choice for many seeking relief from ulcers.